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Table 9Established and Other Potentially Significant Drug InteractionsAlteration in Dose or Regimen May Be Recommended Based on Drug Interaction Studies or Predicted InteractionSee also CLINICAL PHARMACOLOGY for magnitude of interactionWARNINGS and DOSAGE AND ADMINISTRATION
CRIXIVAN is not a cure for HIV-1 infection and patients may continue to experience illnesses associated with HIV-1 infectionincluding opportunistic infectionsPatients should remain under the care of a physician when using CRIXIVAN.
Clinically significant adverse reactionspotentially leading to severelife-threateningor fatal events from greater Citalopram treatment exposures of concomitant medicationsClinically significant adverse reactions from greater exposures of CRIXIVANLoss of therapeutic effect of CRIXIVAN and possible development of resistance.
Patients with hepatic insufficiency due to cirrhosisIn these patientsthe dosage of CRIXIVAN should be lowered because of decreased metabolism of CRIXIVANsee DOSAGE AND ADMINISTRATIONPatients with renal insufficiencyPatients with renal insufficiency have not been studied.
Indinavir is also used sometimes in combination with other medications to treat healthcare workers and other individuals exposed to HIV infection after accidental contact with HIV-contaminated bloodtissuesor other body fluidsTalk to your doctor about the possible risks of using this drug for your condition.
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